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Showing 1–3 of 3 results
Advanced filters: Author: Marcel Hijnen Clear advanced filters

  • Enzyme substrates and products often diffuse too rapidly to assess the catalytic implications of these movements. Here, the authors characterise the structural basis of product and substrate diffusion for an exo-hydrolase and discover a substrate-product assisted processive catalytic mechanism.

    • Victor A. Streltsov
    • Sukanya Luang
    • Maria Hrmova
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • The Gag precursor protein recognizes the HIV-1 genomic RNA among hundreds of other viral and cellular RNAs during assembly of viral particles. Here, the authors identify the primary binding site of Gag on the HIV-1 RNA, and show that other RNA regions enhance or inhibit Gag binding.

    • Ekram W. Abd El-Wahab
    • Redmond P. Smyth
    • Roland Marquet
    Research
    Nature Communications
    Volume: 5, P: 1-13