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Showing 1–2 of 2 results
Advanced filters: Author: Marco Ventin Clear advanced filters

  • The authors demonstrate that plasma exosomes from children with idiopathic short stature contain elevated hsa-miR-17-3p, that disrupts growth signaling and impairs cartilage cell proliferation. A capsaicin-rich diet in rats triggered gut inflammation, increased exosomal miR-17-3p and recapitulated features of idiopathic short stature.

    • Yameng Wang
    • Zhiwen Wu
    • Jingyu Jia
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-22

  • The emergency of a high frequency of early memory T cells has been associated with clinical success of CAR T cell therapy. Here the authors show that target cancer cells stressed by disulfiram/copper complexes and ionizing radiation favour the reprogramming of CAR T cells that acquire memory-like characteristics, associated with prolonged anti-tumor response in preclinical solid tumor models.

    • Yufeng Wang
    • David L. Drum
    • Xinhui Wang
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17