Nature Search

Midbrain node for context-specific vocalisation in fish

The midbrain is a major site for gating vocalization in vertebrates. Here, the authors show midbrain periaqueductal gray neurons in teleost fish with properties like those in mammals, sculpt the acoustic features of context-specific vocal signals.

Eric R. Schuppe
Irene Ballagh
Andrew H. Bass
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-16
Constraints on the volatile distribution within Shackleton crater at the lunar south pole

Observations from the Lunar Orbiter Laser Altimeter reveal the Moon’s Shackleton crater to be an ancient, unusually well-preserved simple crater whose interior walls are younger than its floor and rim; the relative brightness of the floor at 1,064 nanometres is most readily explained by minimal volatile accumulation since crater formation and decreased space weathering due to permanent shadow.

Maria T. Zuber
James W. Head
H. Jay Melosh
Research20 Jun 2012
Nature

Volume: 486, P: 378-381
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species

Hosios et al. demonstrate that inhibition of mechanistic target of rapamycin complex 1 in cells and in tumors in mice leads to a lysosome-dependent but autophagy-independent shift in membrane lipid metabolism, resulting in increased intracellular triglyceride pools.

Aaron M. Hosios
Meghan E. Wilkinson
Brendan D. Manning
Research19 Dec 2022
Nature Metabolism

Volume: 4, P: 1792-1811
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions

Cancer cells adapt their metabolism to survive limited nutrient availability. Here, the authors show that in conditions of limited glucose or glutamine availability, pancreatic ductal adenocarcinoma cells can use collagen-derived proline to foster the TCA cycle and allow cell survival bothin vitro and in vivo.

Orianne Olivares
Jared R. Mayers
Sophie Vasseur
ResearchOpen Access07 Jul 2017
Nature Communications

Volume: 8, P: 1-14
Cerebral small vessel disease genomics and its implications across the lifespan

White matter hyperintensities (WMH) are a common brain-imaging feature of cerebral small vessel disease. Here, the authors carry out a GWAS and followup analyses for WMH-volume, implicating several variants with potential for risk stratification and drug targeting.

Muralidharan Sargurupremraj
Hideaki Suzuki
Stéphanie Debette
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-18
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

Elevated plasma levels of branched chain amino acids detected prior to pancreatic cancer diagnosis may result from whole body tissue breakdown occurring during the early stages of this disease.

Jared R Mayers
Chen Wu
Brian M Wolpin
Research28 Sept 2014
Nature Medicine

Volume: 20, P: 1193-1198
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

A high-resolution reference panel based on whole-genome sequencing data enables accurate imputation of HLA alleles across diverse populations and fine-mapping of HLA association signals for HIV-1 host response.

Yang Luo
Masahiro Kanai
Soumya Raychaudhuri
Research05 Oct 2021
Nature Genetics

Volume: 53, P: 1504-1516
mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci

Ilana Kelsey
Marie Zbinden
Brendan D. Manning
ResearchOpen Access23 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Yang Luo
Masahiro Kanai
Soumya Raychaudhuri
Amendments and Corrections02 Nov 2021
Nature Genetics

Volume: 53, P: 1722

Search

Filter By:

Search

Quick links