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Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

David R. Booth
Margaret Sunde
Mark B. Pepys
Research27 Feb 1997
Nature

Volume: 385, P: 787-793
Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Jaclyn S. Pearson
Cristina Giogha
Elizabeth L. Hartland
Amendments and Corrections13 Feb 2017
Nature Microbiology

Volume: 2, P: 1
Amyloid formation and depolymerization of tumor suppressor p16^INK4a are regulated by a thiol-dependent redox mechanism

The conversion of a soluble protein into polymeric amyloid structures is poorly understood. Here the authors report that the tumor suppressor protein p16^INK4a changes its structure upon oxidation to form aggregated amyloid fibrils, which are fully reversible upon disulfide bond reduction.

Sarah G. Heath
Shelby G. Gray
Christoph Göbl
ResearchOpen Access01 Jul 2024
Nature Communications

Volume: 15, P: 1-16
Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme

Denis Canet
Alexander M. Last
Christopher M. Dobson
Research11 Mar 2002
Nature Structural Biology

Volume: 9, P: 308-315
Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism

Chi L. L. Pham
Anthony Rey
Margaret Sunde
ResearchOpen Access04 May 2016
Scientific Reports

Volume: 6, P: 1-16
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Enteropathogenic Escherichia coli EspL is a cysteine protease that cleaves RHIM-containing proteins and blocks inflammasome signalling during infection.

Jaclyn S. Pearson
Cristina Giogha
Elizabeth L. Hartland
Research13 Jan 2017
Nature Microbiology

Volume: 2, P: 1-10
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Fergus Couch and colleagues report a genome-wide association study for modifiers of breast cancer susceptibility in BRCA1 mutation carriers. They identify a locus at 19p13 associated with breast cancer risk in BRCA1 mutation carriers, and further replication studies identify this locus as associated with estrogen receptor–negative breast cancer in the general population.

Antonis C Antoniou
Xianshu Wang
Fergus J Couch
Research19 Sept 2010
Nature Genetics

Volume: 42, P: 885-892
Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer

Maryrose Constantine
Chu Kong Liew
Boris Martinac
ResearchOpen Access20 Jan 2016
Scientific Reports

Volume: 6, P: 1-11

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Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Amyloid formation and depolymerization of tumor suppressor p16^INK4a are regulated by a thiol-dependent redox mechanism

Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme

Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer

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