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Advanced filters: Author: Maria Isabel Trejo-Zambrano Clear advanced filters

Affinity maturation generates pathogenic antibodies with dual reactivity to DNase1L3 and dsDNA in systemic lupus erythematosus

Antibodies directed against DNA in systemic lupus erythematosus are functionally diverse. This study demonstrates that DNAse1L3 is the primary target of a subset of autoantibodies previously considered specific for double-stranded DNA.

Eduardo Gomez-Bañuelos
Yikai Yu
Felipe Andrade
ResearchOpen Access20 Mar 2023
Nature Communications

Volume: 14, P: 1-14
Differential Treatments Based on Drug-induced Gene Expression Signatures and Longitudinal Systemic Lupus Erythematosus Stratification

Daniel Toro-Domínguez
Raúl Lopez-Domínguez
Marta E. Alarcón-Riquelme
ResearchOpen Access29 Oct 2019
Scientific Reports

Volume: 9, P: 1-9
Application of machine learning algorithms to identify serological predictors of COVID-19 severity and outcomes

Dhakal, Yin, Escarra-Senmarti et al. investigate the associations of antibody biomarkers with recovery or death from COVID-19 using machine learning algorithms. They demonstrate the serological antibody measures, among COVID-19 patients, that predict intubation or death.

Santosh Dhakal
Anna Yin
Sabra L. Klein
ResearchOpen Access26 Nov 2024
Communications Medicine

Volume: 4, P: 1-15

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