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Showing 1–4 of 4 results
Advanced filters: Author: Maria Kanelli Clear advanced filters

  • Intradermal microneedles for the co-delivery of mRNA and near-infrared fluorescent microparticles are used in combination with deep learning-based image analysis for the simultaneous administration of therapeutics and registry of patient information records into the skin.

    • Jooli Han
    • Maria Kanelli
    • Ana Jaklenec
    ResearchOpen Access
    Nature Materials
    Volume: 24, P: 794-803

  • Mucosal vaccines are critical in the fight against mucosal pathogens because they enable the immune system to directly neutralize these pathogens at their primary site of entry. This Review examines the role of material design in addressing the challenges associated with mucosal vaccine delivery.

    • Behnaz Eshaghi
    • Alex Schudel
    • Ana Jaklenec
    Reviews
    Nature Reviews Materials
    Volume: 9, P: 29-45

  • CRISPR–Cas9 technology is a powerful tool for immune cell engineering. Ex vivo editing has progressed to clinical trials, but in vivo applications are still limited owing to delivery challenges. This Review summarizes these challenges as well as strategies and progress in delivering CRISPR–Cas9 to immune and non-immune cells.

    • Shahad K. Alsaiari
    • Behnaz Eshaghi
    • Ana Jaklenec
    Reviews
    Nature Reviews Materials
    Volume: 10, P: 44-61