Kohl et al. combine high-resolution Ribo-seq and cryo electron microscopy to show that the bacterium Staphylococcus aureus uses extended Shine-Dalgarno motifs to initiate translation, which can make start-site decoding incompatible with phylogenetically distant ribosomes.
- Maximilian P. Kohl
- Roberto Bahena-Ceron
- Stefano Marzi
