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Advanced filters: Author: Maria Nenchova Clear advanced filters

  • The authors show that MTCH2 promotes BAX and BAK oligomerization independently of its insertase activity, supporting its role in shaping the mitochondrial lipid environment that enables efficient pore expansion, mitochondrial DNA release and inflammatory signaling.

    • Hector Flores-Romero
    • Aida Pena-Blanco
    • Ana J. Garcia-Saez
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 33, P: 824-837