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Showing 1–3 of 3 results

Advanced filters: Author: Maria Raitses-Gurevich Clear advanced filters

Deep phenotyping of health–disease continuum in the Human Phenotype Project

Deep phenotyping of an ancestrally diverse group of 13,000 individuals in the Human Phenotype Project highlights diversity and variations in lifestyle factors, clinical features and molecular signatures of health and disease.

Lee Reicher
Smadar Shilo
Eran Segal
Research15 Jul 2025
Nature Medicine

Volume: 31, P: 3191-3203
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer

Analysis of messenger RNA splicing in a large cohort of pancreatic ductal adenocarcinoma tumours identifies differential splicing correlating with disease progression, associated with the the splicing regulator RBFOX2.

Amina Jbara
Kuan-Ting Lin
Rotem Karni
ResearchOpen Access22 Mar 2023
Nature

Volume: 617, P: 147-153
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours

A study identifies 41 consensus gene expression meta-programs that are coordinately upregulated in subpopulations of malignant cells across tumour types, providing a comprehensive picture of hallmarks of intratumour heterogeneity.

Avishai Gavish
Michael Tyler
Itay Tirosh
Research31 May 2023
Nature

Volume: 618, P: 598-606