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Advanced filters: Author: Maribel Mosqueda Clear advanced filters

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

KRAS-driven lung cancers represent an aggressive form of NSCLC. In this study the authors perform an in vivo functional screening and identify GATAD2B as a driver of tumor growth and metastasis in KRAS-driven lung cancer.

Caitlin L. Grzeskowiak
Samrat T. Kundu
Kenneth L. Scott
ResearchOpen Access16 Jul 2018
Nature Communications

Volume: 9, P: 1-13
Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

Bar-Eli and colleagues report that CREB-mediated downregulation of the RNA-editing enzyme ADAR1 results in decreased adenosine-to-inosine editing of miR-455-5p, which enhances melanoma growth and metastasis.

Einav Shoshan
Aaron K. Mobley
Menashe Bar-Eli
Research16 Feb 2015
Nature Cell Biology

Volume: 17, P: 311-321

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In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

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