Nature Search

Elevated c-myc expression facilitates the replication of SV40 DNA in human lymphoma cells

Marie Classon
Marie Henriksson
Marie-Louise Hammaskjöld
Research19 Nov 1987
Nature

Volume: 330, P: 272-274
Interim safety and efficacy of gene therapy for RLBP1-associated retinal dystrophy: a phase 1/2 trial

This phase I/II clinical trial was designed to assess safety and efficacy of gene therapy for Bothnia dystrophy, an inherited retinal degeneration leading to blindness. Kvanta et al. show interim results from 12 patients with meaningfully improved visual function in dim light.

Anders Kvanta
Nalini Rangaswamy
Helder André
ResearchOpen Access10 Sept 2024
Nature Communications

Volume: 15, P: 1-12
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis

David Engblom
Sipra Saha
Anders Blomqvist
Research19 Oct 2003
Nature Neuroscience

Volume: 6, P: 1137-1138
Genetic architecture of subcortical brain structures in 38,851 individuals

Genome-wide analysis identifies variants associated with the volume of seven different subcortical brain regions defined by magnetic resonance imaging. Implicated genes are involved in neurodevelopmental and synaptic signaling pathways.

Claudia L. Satizabal
Hieab H. H. Adams
M. Arfan Ikram
Research21 Oct 2019
Nature Genetics

Volume: 51, P: 1624-1636
Novel genetic loci underlying human intracranial volume identified through genome-wide association

In a GWAS study of 32,438 adults, the authors discovered five novel loci for intracranial volume and confirmed two known signals. Variants for intracranial volume were also related to childhood and adult cognitive function and to Parkinson's disease, and enriched near genes involved in growth pathways, including PI3K-AKT signaling.

Hieab H H Adams
Derrek P Hibar
Paul M Thompson
Research03 Oct 2016
Nature Neuroscience

Volume: 19, P: 1569-1582
Novel genetic loci associated with hippocampal volume

The hippocampus in mammalian brain varies in size across individuals. Here, Hibar and colleagues perform a genome-wide association meta-analysis to find six genetic loci with significant association to hippocampus volume.

Derrek P. Hibar
Hieab H. H. Adams
M. Arfan Ikram
ResearchOpen Access18 Jan 2017
Nature Communications

Volume: 8, P: 1-12
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

The tau protein is theorized to spread transneuronally in Alzheimers disease, though this theory remains unproven in humans. Our simulations of epidemic-like protein spreading across human brain networks support this theory, and suggest the spreading dynamics are modified by β-amyloid

Jacob W. Vogel
Yasser Iturria-Medina
Per Wollmer
ResearchOpen Access26 May 2020
Nature Communications

Volume: 11, P: 1-15
A national cohort study of long-term opioid prescription and sociodemographic and health care-related risk factors

Krüger et al. analyze the risk of long-term opioid use in a cohort of over 750,000 Swedish adults after a first prescription. They find that 8.1% continue to use opioids for longer than 3 months, with higher odds among individuals with psychiatric history and those initiating treatment in primary care.

Cecilia Krüger
Johan Franck
Jeanette Westman
ResearchOpen Access17 Sept 2025
Communications Medicine

Volume: 5, P: 1-10
Common genetic variants influence human subcortical brain structures

Genome-wide association studies are used to identify common genetic variants that affect the structure of selected subcortical regions of the human brain; their identification provides insight into the causes of variability in brain development and may help to determine mechanisms of neuropsychiatric dysfunction.

Derrek P. Hibar
Jason L. Stein
Sarah E. Medland
Research21 Jan 2015
Nature

Volume: 520, P: 224-229
The political effects of emergency frames in sustainability

Emergency frames in sustainability debates can stimulate collective action on issues for which it is lacking but can have consequences. This Review examines the political effects of emergency frames in sustainability and develops a typology of different effects to build a shared vocabulary for analysis and decision-making.

James Patterson
Carina Wyborn
Dhanasree Jayaram
Reviews26 Jul 2021
Nature Sustainability

Volume: 4, P: 841-850
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Asha Singanamalli
Haibo Wang
Kristin Fargher
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

Jacob W. Vogel
Yasser Iturria-Medina
Per Wollmer
Amendments and CorrectionsOpen Access05 Aug 2021
Nature Communications

Volume: 12, P: 1
De novo and inherited variants in ZNF292 underlie a neurodevelopmental disorder with features of autism spectrum disorder

Ghayda M. Mirzaa
Jessica X. Chong
Michael J. Bamshad
Research14 Nov 2019
Genetics in Medicine

Volume: 22, P: 538-546
Cinacalcet use and the risk of cardiovascular events, fractures and mortality in chronic kidney disease patients with secondary hyperparathyroidism

Marie Evans
Shona Methven
Juan-Jesus Carrero
ResearchOpen Access01 Feb 2018
Scientific Reports

Volume: 8, P: 1-9
Lower serum calcium is independently associated with CKD progression

Cynthia J. Janmaat
Merel van Diepen
Juan Jesus Carrero
ResearchOpen Access26 Mar 2018
Scientific Reports

Volume: 8, P: 1-9

Search

Elevated c-myc expression facilitates the replication of SV40 DNA in human lymphoma cells

Interim safety and efficacy of gene therapy for RLBP1-associated retinal dystrophy: a phase 1/2 trial

Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis

Genetic architecture of subcortical brain structures in 38,851 individuals

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Novel genetic loci associated with hippocampal volume

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

A national cohort study of long-term opioid prescription and sociodemographic and health care-related risk factors

Common genetic variants influence human subcortical brain structures

The political effects of emergency frames in sustainability

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

De novo and inherited variants in ZNF292 underlie a neurodevelopmental disorder with features of autism spectrum disorder

Cinacalcet use and the risk of cardiovascular events, fractures and mortality in chronic kidney disease patients with secondary hyperparathyroidism

Lower serum calcium is independently associated with CKD progression

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