Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Marie-Emilie Terret Clear advanced filters

  • Verlhac, Terret and colleagues report that softening of the mouse oocyte cortex during meiosis I is needed for spindle migration and positioning. They show that Mos/mAPK signalling triggers myosin II exclusion from the cortex and an Arp2/3-dependent cortical F-actin thickening that contributes to cortical softening.

    • Agathe Chaigne
    • Clément Campillo
    • Marie-Emilie Terret
    Research
    Nature Cell Biology
    Volume: 15, P: 958-966

  • The developmental potential of human and murine oocytes is predicted by their mechanical properties. Here the authors show that artificial reduction of cortex tension produces aneuploid mouse oocytes and speculate that this may contribute to the high aneuploidy rate typical of female meiosis.

    • Isma Bennabi
    • Flora Crozet
    • Marie-Emilie Terret
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • How the mitotic spindle is positioned in the centre of the cell during the first mitotic division is not clear. Here Chaigne et al.show that the pronucleus coarsely centres using F-actin/Myosin-Vb dynamics, and the metaphase plate is finely centred by an F-actin cage influenced by high cortical tension.

    • Agathe Chaigne
    • Clément Campillo
    • Marie-Emilie Terret
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-14

  • Cytoskeletal activity generates mechanical forces known to agitate and displace membrane-bound organelles in the cytoplasm. In oocytes, Al Jord et al. discover that these cytoplasmic forces functionally remodel nuclear RNA-processing condensates across scales for developmental success.

    • Adel Al Jord
    • Gaëlle Letort
    • Marie-Hélène Verlhac
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-19

  • During anaphase, the cysteine protease separase cleaves cohesin and releases sister chromatids. In budding yeast, separase also has a crucial non-proteolytic role in triggering mitotic exit. Separase performs a similar non-catalytic function in frog and mouse oocytes through its physical interaction with cdk1. Vertebrate separase is therefore essential not only for homologue disjunction, but also for bringing about the end of meiosis I.

    • Marie-Emilie Terret
    • Prasad V. Jallepalli
    News & Views
    Nature Cell Biology
    Volume: 8, P: 910-911

  • Asymmetric spindle positioning in female mouse meiosis depends on the assembly of actin networks. Here, Chaigne et al. show by theoretical modelling and artificial manipulation of the oocyte cortex that a narrow stiffness regime is required to correctly position the spindle during meiosis I in the mouse oocyte.

    • A. Chaigne
    • C. Campillo
    • M. E. Terret
    Research
    Nature Communications
    Volume: 6, P: 1-10

  • Cohesin inhibits the transcriptional machinery's interaction with and movement along chromatin, but does not prevent replication forks from duplicating the genome in S phase. Using single-molecule analysis, a replication complex is now found to affect acetylation of a subunit of cohesin, and this acetylation appears to be a central determinant of fork processivity. Loss of this regulatory mechanism leads to the spontaneous accrual of DNA damage.

    • Marie-Emilie Terret
    • Rebecca Sherwood
    • Prasad V. Jallepalli
    Research
    Nature
    Volume: 462, P: 231-234