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Showing 1–13 of 13 results
Advanced filters: Author: Marion Silies Clear advanced filters

  • For young glia to migrate along motor axons in the developing fly, their adhesion to the axon must be broken. Silies and Klämbt show that this is accomplished by removal of Fas2 from the axonal membrane, involving a ubiquitin ligase complex that has previously been implicated only in cell cycle regulation.

    • Marion Silies
    • Christian Klämbt
    Research
    Nature Neuroscience
    Volume: 13, P: 1357-1364

  • The Drosophila visual system first computes motion in the dendrites of T4 and T5 neurons via a linear mechanism that uses ON and OFF information. Here, the authors show that the Tm9, Tm2, and CT1 neurons provide both ON and OFF information to direction-selective T5 cells in the OFF pathway.

    • Giordano Ramos-Traslosheros
    • Marion Silies
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Whether there is an exception to the homogenous wiring rule in visual systems remain largely unknown. Here authors reveal heterogeneity in the synaptic connectivity of cell types in the fly eye. Thus, parallel units of the eye will compute the same visual input differently.

    • Jacqueline Cornean
    • Sebastian Molina-Obando
    • Marion Silies
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • An analysis of the Drosophila connectome yields all cell types intrinsic to the optic lobe, and their rules of connectivity.

    • Arie Matsliah
    • Szi-chieh Yu
    • Gregory S. X. E. Jefferis
    ResearchOpen Access
    Nature
    Volume: 634, P: 166-180

  • Current models of how animals estimate motion involve correlations between pairs of points in space and time. Here the authors show that both fly and human visual systems can encode the direction and contrast polarity of moving edges using three-point correlations, and that this enhances motion estimation accuracy.

    • Damon A Clark
    • James E Fitzgerald
    • Thomas R Clandinin
    Research
    Nature Neuroscience
    Volume: 17, P: 296-303

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • Dopamine is synonymous with reward in mammals but associated with aversive reinforcement in insects, where reward seems to be signalled by octopamine; here it is shown that flies have discrete populations of dopamine neurons representing positive or negative values that are coordinately regulated by octopamine.

    • Christopher J. Burke
    • Wolf Huetteroth
    • Scott Waddell
    Research
    Nature
    Volume: 492, P: 433-437

  • A genetic platform allows refinement of tissue-specific expression using the upstream activating sequence–GAL4 system in Drosophila melanogaster, facilitating the segmentation of complex expression patterns and allowing GAL4 expression patterns to be repurposed.

    • Daryl M Gohl
    • Marion A Silies
    • Thomas R Clandinin
    Research
    Nature Methods
    Volume: 8, P: 231-237