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Showing 1–2 of 2 results
Advanced filters: Author: Marion Splittgerber Clear advanced filters

  • T box transcription factor Eomesodermin (EOMES) is induced when naïve T cells are converted to innate memory T cells in response to cytokines. Here the authors show that EOMES is recruited to RUNX3-bound enhancers and interacts with BRG1 during innate memory T cell formation.

    • Nicolas Istaces
    • Marion Splittgerber
    • Abdulkader Azouz
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • Detavernier et al. show that localized waves of epigenetic programming regulate the differentiation process of Ly6Chi monocytes during oral infection by Toxoplasma gondii, which are dominated by STAT1 in the bone marrow and AP-1/NF-kB in the periphery. This study provides insight into how monocytes are differentiated in response to inflammatory cues.

    • Aurélie Detavernier
    • Abdulkader Azouz
    • Stanislas Goriely
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-14