The ventral tegmental area (VTA) and lateral habenula (LHb) are reciprocally connected. Here the authors show, using electron microscopy, tract tracing and optogenetics in rodents, that the majority of VTA neurons innervating LHb release both GABA and glutamate at the same synaptic terminals.
- David H Root
- Carlos A Mejias-Aponte
- Marisela Morales
