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Showing 1–6 of 6 results
Advanced filters: Author: Marissa Suarez Clear advanced filters

  • Laser capture microdissection is a technique that uses a highly precise laser to isolate and collect specific cells from a tissue sample. In this Primer, Liotta et al. discuss the use of laser capture microdissection in clinical research and its potential in future personalized therapies.

    • Lance A. Liotta
    • Thomas P. Conrads
    • Emanuel F. Petricoin
    Reviews
    Nature Reviews Methods Primers
    Volume: 5, P: 1-23

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Crystallography and mutagenesis analyses examine how HIV-1 Nef interacts with AP2 to enable CD4 binding and downregulation and reveal the role of a Nef pocket that is also involved in downregulation of class I MHC.

    • Yonghwa Kwon
    • Robyn M. Kaake
    • Xiaofei Jia
    Research
    Nature Structural & Molecular Biology
    Volume: 27, P: 822-828

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103