Nature Search

NIS-Seq enables cell-type-agnostic optical perturbation screening

An optical pooled screening method can correlate phenotypes and perturbations in any nucleated cell type.

Caroline I. Fandrey
Marius Jentzsch
Jonathan L. Schmid-Burgk
ResearchOpen Access19 Dec 2024
Nature Biotechnology

Volume: 43, P: 1337-1347
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

SARS-CoV-2 detection with LAMP-Seq combines isothermal amplification and barcoding with high-throughput sequencing.

Kerstin U. Ludwig
Ricarda M. Schmithausen
Jonathan L. Schmid-Burgk
Research29 Jun 2021
Nature Biotechnology

Volume: 39, P: 1556-1562
Design principles for cyclin K molecular glue degraders

Detailed analysis of the structure–activity relationship for cyclin K degraders reveals diverse compounds that acquire glue activity through simultaneous binding to the CDK12 kinase pocket and engagement of several key DDB1 interfacial residues.

Zuzanna Kozicka
Dakota J. Suchyta
Nicolas H. Thomä
ResearchOpen Access07 Sept 2023
Nature Chemical Biology

Volume: 20, P: 93-102
Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.

Lena Lampe
Marius Jentzsch
Elena A. Levashina
ResearchOpen Access10 Dec 2019
Nature Communications

Volume: 10, P: 1-10
Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation

Juliane Grimm
Marius Bill
Sebastian Schwind
Research30 Nov 2018
Bone Marrow Transplantation

Volume: 54, P: 1189-1197
Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

Kerstin U. Ludwig
Ricarda M. Schmithausen
Jonathan L. Schmid-Burgk
Amendments and Corrections18 Jul 2022
Nature Biotechnology

Volume: 40, P: 1295
Prognostic impact of measurable residual clonal hematopoiesis in acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation

Lara Bischof
Jule Ussmann
Madlen Jentzsch
ResearchOpen Access25 Oct 2023
Leukemia

Volume: 38, P: 198-201
ELN risk stratification and outcomes in secondary and therapy-related AML patients consolidated with allogeneic stem cell transplantation

Madlen Jentzsch
Juliane Grimm
Sebastian Schwind
ResearchOpen Access19 Nov 2020
Bone Marrow Transplantation

Volume: 56, P: 936-945
Prognostic relevance of remission and measurable residual disease status in AML patients prior to reduced intensity or non-myeloablative allogeneic stem cell transplantation

Madlen Jentzsch
Juliane Grimm
Sebastian Schwind
CorrespondenceOpen Access29 Apr 2021
Blood Cancer Journal

Volume: 11, P: 1-4
Measurable residual disease of canonical versus non-canonical DNMT3A, TET2, or ASXL1 mutations in AML at stem cell transplantation

Madlen Jentzsch
Juliane Grimm
Sebastian Schwind
CorrespondenceOpen Access15 Jul 2021
Bone Marrow Transplantation

Volume: 56, P: 2610-2612
Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non-myeloablative conditioning hematopoietic stem cell transplantation

Laura K. Schmalbrock
Lynn Bonifacio
Sebastian Schwind
Correspondence15 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 640-643

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NIS-Seq enables cell-type-agnostic optical perturbation screening

LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

Design principles for cyclin K molecular glue degraders

Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation

Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

Prognostic impact of measurable residual clonal hematopoiesis in acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation

ELN risk stratification and outcomes in secondary and therapy-related AML patients consolidated with allogeneic stem cell transplantation

Prognostic relevance of remission and measurable residual disease status in AML patients prior to reduced intensity or non-myeloablative allogeneic stem cell transplantation

Measurable residual disease of canonical versus non-canonical DNMT3A, TET2, or ASXL1 mutations in AML at stem cell transplantation

Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non-myeloablative conditioning hematopoietic stem cell transplantation

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