Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Mark Tullett Clear advanced filters

  • Analysis of the somatic and transcriptomic profile of 123 acral melanoma samples from Mexican patients helps understand tumour origins and prognosis, and highlights the importance of including samples from diverse ancestries in cancer genomics studies.

    • Patricia Basurto-Lozada
    • Martha Estefania Vázquez-Cruz
    • Carla Daniela Robles-Espinoza
    ResearchOpen Access
    Nature
    Volume: 651, P: 221-230

  • Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterogeneity in metastases from different organs.

    • Roy Rabbie
    • Naser Ansari-Pour
    • David J. Adams
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Louise van der Weyden et al. report a CRISPRa screen in mice to identify membrane protein-encoding genes that, when overexpressed, enhance the metastatic potential of melanoma cells. They find that high expression of LRRN4CL in melanoma cells increases lung metastases in mice and correlates with poorer survival in melanoma patients, suggesting it could be a promising drug target.

    • Louise van der Weyden
    • Victoria Harle
    • David J. Adams
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12