This paper shows that the parasite Trypanosoma brucei is able to establish infection in flies by penetrating the protective peritrophic matrix in the fly midgut at the place of matrix secretion in the proventriculus. Such early proventricular colonization is potentiated by factors that are present in trypanosome-infected blood ingested by the flies.
- Clair Rose
- Aitor Casas-Sánchez
- Álvaro Acosta-Serrano