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Showing 1–9 of 9 results

Advanced filters: Author: Marlon Stoeckius Clear advanced filters

Passenger mutations link cellular origin and transcriptional identity in human lung adenocarcinomas

This study shows how the links between somatic passenger mutations in tumors and normal cell transcriptomes can be used to infer cell-of-origin in lung adenocarcinoma.

Sukanya Panja
Padmaja Mantri
Marcin Imieliński
Research27 Nov 2025
Nature Genetics

Volume: 57, P: 3066-3074
Tonic type I interferon signaling optimizes the antiviral function of plasmacytoid dendritic cells

Pucella, Maqueda-Alfaro and colleagues distinguish three developmentally related subsets of mouse plasmacytoid dendritic cells that differ in their ability to produce type I interferon and their susceptibility to virus.

Joseph N. Pucella
Raul A. Maqueda-Alfaro
Boris Reizis
ResearchOpen Access14 Oct 2025
Nature Immunology

Volume: 26, P: 1946-1961
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression

Fluorescence-activated cell sorting of worm embryos promises to replace manual sorting of staged embryos and yields large populations highly enriched in specific developmental stages, allowing high-throughput genomic analysis.

Marlon Stoeckius
Jonas Maaskola
Nikolaus Rajewsky
Research06 Sept 2009
Nature Methods

Volume: 6, P: 745-751
Integration of whole transcriptome spatial profiling with protein markers

Visium spatial transcriptomics is combined with markers for more than 30 proteins.

Nir Ben-Chetrit
Xiang Niu
Dan A. Landau
Research02 Jan 2023
Nature Biotechnology

Volume: 41, P: 788-793
Publisher Correction: A RORγt⁺ cell instructs gut microbiota-specific T_reg cell differentiation

Ranit Kedmi
Tariq A. Najar
Dan R. Littman
Amendments and Corrections23 Sept 2022
Nature

Volume: 610, P: E7
Tracing tumorigenesis in a solid tumor model at single-cell resolution

Understanding tumour development at a granular level is a challenge in solid tumours. Here, the authors provide a cell atlas across tumour development in a genetic model of salivary gland squamous cell carcinoma using single-cell transcriptome and epitope profiling.

Samantha D. Praktiknjo
Benedikt Obermayer
Nikolaus Rajewsky
ResearchOpen Access20 Feb 2020
Nature Communications

Volume: 11, P: 1-12
A RORγt⁺ cell instructs gut microbiota-specific T_reg cell differentiation

Induction of T regulatory cells by gut microbes is mediated by antigen-presenting RORγt⁺ cells, unlike that of T follicular helper and T helper 17 cells, which requires different cell types.

Ranit Kedmi
Tariq A. Najar
Dan R. Littman
Research07 Sept 2022
Nature

Volume: 610, P: 737-743
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells

ECCITE-seq combines the single-cell analysis of multiple modalities, for example transcriptome, immune cell receptors, cell surface proteins and single-guide RNAs.

Eleni P. Mimitou
Anthony Cheng
Peter Smibert
Research22 Apr 2019
Nature Methods

Volume: 16, P: 409-412
Simultaneous epitope and transcriptome measurement in single cells

Using established high-throughput single-cell RNA-seq platforms, CITE-seq combines highly multiplexed, antibody-based protein marker quantification with unbiased transcriptome profiling for thousands of single cells.

Marlon Stoeckius
Christoph Hafemeister
Peter Smibert
Research31 Jul 2017
Nature Methods

Volume: 14, P: 865-868