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Showing 1–5 of 5 results
Advanced filters: Author: Marta Maglione Clear advanced filters
  • The physical distance between synaptic Ca2+ channels and sensors modulates short-term plasticity (STP). Here, the authors show that synaptic release factors Unc13A and Unc13B distinctly couple with Ca2+ channels and contribute to the neural decoding of distinct sensory information in Drosophila.

    • Atefeh Pooryasin
    • Marta Maglione
    • Stephan J. Sigrist
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14
  • The role of macroautophagy in neuronal processes mediating brain maintenance remains enigmatic. Authors show here that impairing autophagy within the major learning related brain center of Drosophila, and not other regions, triggered a form of presynaptic metaplasticity that was invariably connected to the absence of the specific component of aversive olfactory memory, which normally only declines in the course of aging process

    • Anuradha Bhukel
    • Christine Brigitte Beuschel
    • Stephan J. Sigrist
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13
  • Temporally stochastic STED nanoscopy with electro-optical deflector–based scanning allows ultrafast super-resolution imaging. The method was used to monitor vesicles and viruses moving at ~2 μm/s with no motion blur.

    • Jale Schneider
    • Jasmin Zahn
    • Stefan W Hell
    Research
    Nature Methods
    Volume: 12, P: 827-830
  • Standard light microscopy techniques cannot resolve the subcellular structures of neurons: axons, presynaptic active zones, postsynaptic densities and dendritic spines. In this review, the authors discuss the use of recently developed super-resolution light microscopic techniques to resolve these structures, and how such techniques can be most effectively used in the future.

    • Marta Maglione
    • Stephan J Sigrist
    Reviews
    Nature Neuroscience
    Volume: 16, P: 790-797