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Showing 1–5 of 5 results
Advanced filters: Author: Marta Majkut Clear advanced filters

  • Porosity is a key issue in additive manufacturing (AM). Here, the authors reveal the bubble evolution mechanisms including formation, coalescence, pushing, growth, entrainment, escape, and entrapment during directed energy deposition AM using in situ X-ray imaging and multiphysics modelling.

    • Kai Zhang
    • Yunhui Chen
    • Peter D. Lee
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Targeted protein degradation via CRBN-modulating molecular glues has revolutionized therapeutic strategies, yet challenges remain in expanding their substrate scope. Here, the authors identify novel CRBN substrates and develop ABS-752, a prodrug activated in cirrhotic liver, demonstrating potent anti-cancer activity against hepatocellular carcinoma.

    • Przemysław Glaza
    • Roman Pluta
    • Michał J. Walczak
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-15

  • Ferroelectricity can be modified by domain wall strain fields that extend over nanometres. Here, with X-ray microscopy, strain fields over several micrometres are observed in BaTiO3, suggesting ferroelectricity is globally altered throughout the material.

    • Hugh Simons
    • Astri Bjørnetun Haugen
    • Henning Friis Poulsen
    Research
    Nature Materials
    Volume: 17, P: 814-819

  • Load partitioning to grains during deformation of a polycrystalline material is affected by the presence of twins. Here, synchrotron diffraction is used to study 1300 twin-parent grains, revealing that stress is higher in twins than in the parent grain during the early stages of plastic deformation.

    • Karim Louca
    • Hamidreza Abdolvand
    • Jonathan Wright
    ResearchOpen Access
    Communications Materials
    Volume: 2, P: 1-11