Psychotropic medication use, unhealthy lifestyle behaviors and polygenic risk for high body mass index (PGS-BMI) may elevate cardiovascular disease (CVD) risk in individuals with mental illness. In this study, the authors analyze UK Biobank data, revealing that psychotropic users with high PGS-BMI and unhealthy lifestyles face the greatest BMI and CVD risk, highlighting the need for targeted interventions.
- Nini de Boer
- Iris Hanskamp
- Jurjen J. Luykx