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Showing 1–10 of 10 results
Advanced filters: Author: Martial Balland Clear advanced filters

  • Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of centriole separation.

    • Elisa Vitiello
    • Philippe Moreau
    • Martial Balland
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Cells probe and respond to their physical environment by exerting force on their surroundings. Here Mandal et al.grow cells in the same shape and area but on different adhesive patterns to show that they integrate information on extra-cellular matrix geometry at the whole-cell level.

    • Kalpana Mandal
    • Irène Wang
    • Martial Balland
    Research
    Nature Communications
    Volume: 5, P: 1-10

  • The mechanical properties of biological tissues are key to their integrity and function. Here, the authors engineer 3D microtissues from optogenetically modified fibroblasts and use light to quantify tissue elasticity and strain propagation using their own constituent cells as internal actuators.

    • Adrien Méry
    • Artur Ruppel
    • Thomas Boudou
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • The immune synapse promotes cellular information exchange but the role of biophysical forces in synapse function is unclear. Here, the authors show that B cells exert two types of forces, a centripetal myosin II-driven force and a central actin protrusive force at the site of antigen extraction.

    • Anita Kumari
    • Judith Pineau
    • Paolo Pierobon
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al. provide evidence of an ECM stiffnessmodulated role of Optineurin (OPTN), which regulates HACE1-dependant Rac1 activity and thus controls integrinmediated mechanotransduction and bacterial invasion.

    • Serena Petracchini
    • Daniel Hamaoui
    • Amel Mettouchi
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-22

  • Cell–cell adhesion molecules and the cytoskeleton determine endothelial cell shape during the formation of blood vessels. Here the authors show that the scaffold protein, amotL2, couples adherens junctions to contractile cytoskeletal proteins to coordinate cellular morphogenesis with aortic lumen expansion.

    • Sara Hultin
    • Yujuan Zheng
    • Lars Holmgren
    Research
    Nature Communications
    Volume: 5, P: 1-13

  • It is unclear how cell adhesion and elongation coordinate during formation of bacterial microcolonies. Here, Duvernoy et al. monitor microcolony formation in rod-shaped bacteria, and show that patterns of surface colonization derive from the spatial distribution of adhesive factors on the cell envelope.

    • Marie-Cécilia Duvernoy
    • Thierry Mora
    • Nicolas Desprat
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10