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Showing 1–2 of 2 results
Advanced filters: Author: Martin Baunach Clear advanced filters

  • The biosynthesis of xiamycin, an antimicrobial bacterial indolosesquiterpenoid, involves an unusual cyclization cascade. Here, the authors characterise the XiaF enzyme, which resembles xenobiont-degrading enzymes and is responsible for a hidden indole hydroxylation step that triggers the cyclization reaction.

    • Susann Kugel
    • Martin Baunach
    • Christian Hertweck
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13

  • Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding identification of natural product biosynthetic origins and metabolite structures.

    • Michelle A. Schorn
    • Stefan Verhoeven
    • Justin J. J. van der Hooft
    Comments & OpinionOpen Access
    Nature Chemical Biology
    Volume: 17, P: 363-368