Nature Search

Correction: Radiation enteropathy—pathogenesis, treatment and prevention

Martin Hauer-Jensen
James W. Denham
H. Jervoise N. Andreyev
Amendments and Corrections26 Aug 2014
Nature Reviews Gastroenterology & Hepatology

Volume: 11, P: 578
Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

Using an unbiased genetic screen in mice, Hartmut Geiger et al. found that the thrombomodulin–activated protein C pathway, which controls blood coagulation among other functions, also protects from radiation damage. Administration of a recombinant variant of thrombomodulin or of recombinant activated protein C protected mice from total body irradiation, pointing to potential therapeutic applications.

Hartmut Geiger
Snehalata A Pawar
Martin Hauer-Jensen
Research24 Jun 2012
Nature Medicine

Volume: 18, P: 1123-1129
Radiation enteropathy—pathogenesis, treatment and prevention

Radiation enteropathy remains an important obstacle to uncomplicated cancer cures after radiation therapy of pelvic and abdominal malignancies. Moreover, the prevalence of radiation enteropathy in the population exceeds that of IBD. This Review introduces the clinical problem of radiation enteropathy, discusses contemporary concepts in pathogenesis, current therapeutic options and strategies for development of new radioprotective agents.

Martin Hauer-Jensen
James W. Denham
H. Jervoise N. Andreyev
Reviews01 Apr 2014
Nature Reviews Gastroenterology & Hepatology

Volume: 11, P: 470-479
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

A small-molecule inducer of apoptosis is able to kill senescent cells in the bone marrow of irradiated or aged mice, thereby improving hematopoietic stem cell function.

Jianhui Chang
Yingying Wang
Daohong Zhou
Research14 Dec 2015
Nature Medicine

Volume: 22, P: 78-83
Identification of novel breakpoints for locus- and region-specific translocations in 293 cells by molecular cytogenetics before and after irradiation

Regina L. Binz
Erming Tian
Rupak Pathak
ResearchOpen Access22 Jul 2019
Scientific Reports

Volume: 9, P: 1-10
Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol

Vijay K. Singh
Stephen Y. Wise
Thomas M. Seed
ResearchOpen Access10 Jun 2024
Scientific Reports

Volume: 14, P: 1-20
Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol

Vijay K. Singh
Stephen Y. Wise
Thomas M. Seed
ResearchOpen Access08 Mar 2024
Scientific Reports

Volume: 14, P: 1-18
C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress

Sudip Banerjee
Qiang Fu
Snehalata A. Pawar
ResearchOpen Access27 Sept 2019
Scientific Reports

Volume: 9, P: 1-12

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