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Showing 1–3 of 3 results
Advanced filters: Author: Martin Modrak Clear advanced filters

  • Dysregulation of the T cell compartment is a driving factor in the development of Type 1 diabetes (T1D). Here, the authors present a single-cell gene expression analysis of peripheral blood T cells collected from children with T1D at the time of diagnosis and after one year and report an association with impaired T cell effector differentiation and regulatory T cell dysfunction that contribute to the loss of self-tolerance.

    • Veronika Niederlova
    • Ales Neuwirth
    • Ondrej Stepanek
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • Bacterial nanotubes and other similar membranous structures have been reported to function as conduits between cells to exchange DNA, proteins, and nutrients. Here the authors provide evidence that bacterial nanotubes are formed only by dead or dying cells, thus questioning their previously proposed functions.

    • Jiří Pospíšil
    • Dragana Vítovská
    • Libor Krásný
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12