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Showing 1–2 of 2 results
Advanced filters: Author: Martin Schwaderer Clear advanced filters

  • Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensable for higher order chromatin organization.

    • Stephan Nothjunge
    • Thomas G. Nührenberg
    • Ralf Gilsbach
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9

  • How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify distinct epigenetic programs regulating these processes.

    • Ralf Gilsbach
    • Martin Schwaderer
    • Lutz Hein
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14