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Showing 1–3 of 3 results
Advanced filters: Author: Martti Maimets Clear advanced filters

  • The small intestine forms via crosstalk between epithelial and mesenchymal cell compartments. Here, the authors show that a gradient of Wnt signalling along the anterior-posterior axis regulates Sonic Hedgehog which is required for correct formation and regionalization of the small intestine.

    • Martti Maimets
    • Marianne Terndrup Pedersen
    • Kim B. Jensen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Lineage tracing, biophysical modelling and intestinal transplantation approaches are used to demonstrate that, in the mouse fetal intestinal epithelium, cells are highly plastic with respect to cellular identity and, independent of LGR5 expression and cell position, can contribute to the adult stem cell compartment.

    • Jordi Guiu
    • Edouard Hannezo
    • Kim B. Jensen
    Research
    Nature
    Volume: 570, P: 107-111