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Showing 1–5 of 5 results
Advanced filters: Author: Marvin Thielert Clear advanced filters

  • Here, the authors employ cell sorting and sensitive mass spectrometry to generate a comprehensive proteomic and phosphoproteomic resource, revealing inflammation responses and cell-specific signaling, advancing our understanding of islet biology in health and disease.

    • Marvin Thielert
    • Adrian Villalba
    • Raphaël Scharfmann
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-12

  • Recent technological advances in mass spectrometry promise to add single-cell proteomics to the biologist’s toolbox. Here we discuss the current status and what is needed for this exciting technology to lead to biological insight — alone or as a complement to other omics technologies.

    • Florian A. Rosenberger
    • Marvin Thielert
    • Matthias Mann
    Comments & Opinion
    Nature Methods
    Volume: 20, P: 320-323

  • Cell-type-resolved spatial proteomics of the skin from patients with toxic epidermal necrolysis reveals that it is driven by JAK/STAT signaling, leading to successful treatment of this potentially fatal condition in patients using JAK inhibitors.

    • Thierry M. Nordmann
    • Holly Anderton
    • Matthias Mann
    ResearchOpen Access
    Nature
    Volume: 635, P: 1001-1009