Rapid chromosome movements support the side-by-side alignment of the homologous chromosomes during meiotic prophase. Here, the authors show that absence of BAF-1–VRK-1 mediated release of meiotic chromosomes during ongoing movements leads to chromosome abnormalities, a reduced oocyte pool and genome instability.
- Dimitra Paouneskou
- Antoine Baudrimont
- Verena Jantsch