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Cell Death & Disease (2)
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Advanced filters: Author: Marzia Perluigi Clear advanced filters

Aberrant protein networks in Alzheimer disease

Use of a proteomics approach has demonstrated that changes in protein expression association with Alzheimer disease are not always reflected in changes in RNA levels, highlighting the importance of directly studying proteomic changes to a full understanding of Alzheimer disease pathogenesis.

Marzia Perluigi
Eugenio Barone
News & Views17 Mar 2022
Nature Reviews Neurology

Volume: 18, P: 255-256
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

Lung cancer is a very aggressive tumor that often forms brain metastases. We show that lung cancer cells motility, fundamental for the formation of metastases, is controlled by amino acids such as serine and glycine, abundant in brain microenvironment.

Amani Bouzidi
Maria Chiara Magnifico
Francesca Cutruzzolà
ResearchOpen Access26 Nov 2020
Cell Death & Disease

Volume: 11, P: 1-14
Sorcin is an early marker of neurodegeneration, Ca²⁺ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases

Ilaria Genovese
Flavia Giamogante
Gianni Colotti
ResearchOpen Access15 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-18

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