This paper describes the homeodomain transcription factor Skn-1a as a specification factor for a subset of taste receptor cells (TRCs). Mice lacking functional Skn-1a did not have TRCs or behavioral response to sweet, umami and bitter tastes, but instead had more TRCs that detect sour taste.
- Ichiro Matsumoto
- Makoto Ohmoto
- Keiko Abe