Larsen et al. find that presynaptic NMDA receptors at neocortical synapses are heteromeric receptors containing the developmentally expressed NR3A subunit. Their data also indicate that NR3A-containing presynaptic NMDARs mediate tonic presynaptic activity, synaptic transmission and spike timing–dependent plasticity.
- Rylan S Larsen
- Rebekah J Corlew
- Benjamin D Philpot
