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Unique Loss of the PYHIN Gene Family in Bats Amongst Mammals: Implications for Inflammasome Sensing

Matae Ahn
Jie Cui
Lin-Fa Wang
ResearchOpen Access24 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host

Dampened activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome in bat primary immune cells in response to infection with multiple zoonotic viruses is caused by decreased transcriptional priming, the presence of a unique splice variant and an altered leucine-rich repeat domain of bat NLRP3.

Matae Ahn
Danielle E. Anderson
Lin-Fa Wang
Research25 Feb 2019
Nature Microbiology

Volume: 4, P: 789-799
Lessons from the host defences of bats, a unique viral reservoir

Unique biological traits of bats and adaptive evolution associated with flight confer immunotolerance of viral infection that may help to make bats special reservoir hosts for viruses.

Aaron T. Irving
Matae Ahn
Lin-Fa Wang
Reviews20 Jan 2021
Nature

Volume: 589, P: 363-370
Immunophenotyping monocytes, macrophages and granulocytes in the Pteropodid bat Eonycteris spelaea

Akshamal M. Gamage
Feng Zhu
Lin-Fa Wang
ResearchOpen Access15 Jan 2020
Scientific Reports

Volume: 10, P: 1-16
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages

Peng Zhou
Yok Teng Chionh
Lin-Fa Wang
ResearchOpen Access09 Dec 2016
Scientific Reports

Volume: 6, P: 1-10

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