Chronic obstructive pulmonary disease (COPD) is a common, destructive and pre-malignant airway disease often seen in smokers. We know remarkably little about the underlying driving mechanisms. Scientists have recently made important observations indicating that epithelial to mesenchymal transition (EMT) is central to these pathologies, with heparin-binding EGF-like growth factor as an emerging novel therapeutic target to ameliorate EMT in smokers and patients with COPD.
- Mathew Suji Eapen
- Pawan Sharma
- Sukhwinder Singh Sohal
