(+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile) is a plant hormone involved in plant development and stress response that signals through a COI1–JAZ co-receptor complex. Structure-guided design led to the identification of a coronatine derivative that antagonizes the COI1-JAZ interaction and blocks jasmonate signaling in plants.
- Isabel Monte
- Mats Hamberg
- Roberto Solano
