Jonathan Fletcher and colleagues describe highly recurrent deletions of the large muscular dystrophy–associated gene DMD in gastrointestinal stromal tumors, rhabdomyosarcomas and leiomyosarcomas, all cancers with muscle differentiation. Re-expression of DMD in these tumor cells inhibits aspects of their metastatic phenotypes.
- Yuexiang Wang
- Adrian Marino-Enriquez
- Jonathan A Fletcher
