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Functional synapses between neurons and small cell lung cancer

Small cell lung cancer cells form functional synapses with glutamatergic neurons, receiving synaptic transmissions and deriving a proliferative advantage from these interactions.

Vignesh Sakthivelu
Anna Schmitt
Filippo Beleggia
ResearchOpen Access10 Sept 2025
Nature

Volume: 646, P: 1243-1253
SARS-CoV-2 vaccine breakthrough infections with the alpha variant are asymptomatic or mildly symptomatic among health care workers

Several COVID-19 vaccines have shown good efficacy in clinical trials. Here, the authors provide real world effectiveness data in a group of BNT162b2 vaccinated health care workers and find that breakthrough infections are asymptomatic or mild.

Francesca Rovida
Irene Cassaniti
Fausto Baldanti
ResearchOpen Access15 Oct 2021
Nature Communications

Volume: 12, P: 1-7
Publisher Correction: Functional synapses between neurons and small cell lung cancer

Vignesh Sakthivelu
Anna Schmitt
Filippo Beleggia
Amendments and CorrectionsOpen Access19 Sept 2025
Nature

Volume: 646, P: E17
Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

Emerging SARS-CoV-2 variants of concern (VOCs) raises concerns regarding vaccine efficacy. Here, the authors evaluate the neutralizing antibody, and cellular response elicited following inactivated vaccine immunization, and mRNA booster, against the Omicron variant.

Fanglei Zuo
Hassan Abolhassani
Qiang Pan-Hammarström
ResearchOpen Access13 May 2022
Nature Communications

Volume: 13, P: 1-8
LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

Brown adipose tissue (BAT) thermogenesis counteracts obesity and promotes metabolic health. The role of long non-coding RNAs (lncRNAs) in the regulation of this process is not well understood. Here the authors identify a maternally expressed lncRNA, H19, that increases BAT oxidative metabolism and energy expenditure.

Elena Schmidt
Ines Dhaouadi
Jan-Wilhelm Kornfeld
ResearchOpen Access06 Sept 2018
Nature Communications

Volume: 9, P: 1-16
Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled

Camilla Aurora Franchino
Elisa Motori
Matteo Bergami
Research HighlightsOpen Access01 Jan 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-2
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia

In a phase 1/2 clinical trial, gene therapy with autologous hematopoietic stem cells significantly reduced transfusion requirement in adults and children with transfusion dependent ß-thalassemia.

Sarah Marktel
Samantha Scaramuzza
Giuliana Ferrari
Research21 Jan 2019
Nature Medicine

Volume: 25, P: 234-241

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Functional synapses between neurons and small cell lung cancer

SARS-CoV-2 vaccine breakthrough infections with the alpha variant are asymptomatic or mildly symptomatic among health care workers

Publisher Correction: Functional synapses between neurons and small cell lung cancer

Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled

Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia

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