The expression of the nucleolar protein nucleophosmin (NPM) decreases during the differentiation of various cell types. Here, the authors show that the collaboration between the RNA-binding proteins, HuR and KSRP, reduces the stability of NPM mRNA in myoblasts, thereby allowing myogenesis.
- Anne Cammas
- Brenda Janice Sanchez
- Imed-Eddine Gallouzi