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Showing 1–6 of 6 results
Advanced filters: Author: Matthew B. Veldman Clear advanced filters
  • In preclinical studies, the FDA approved TSP-1 antagonist gabapentin has been shown to disrupt neuronal-glioma interactions, slowing glioblastoma progression. Here, authors report a retrospective cohort study demonstrating a survival benefit associated with gabapentin in patients with newly diagnosed glioblastoma.

    • Joshua D. Bernstock
    • Mulki Mehari
    • Shawn L. Hervey-Jumper
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-6
  • Most neuronal reconstruction software can automatically trace single neuronal morphologies but tracing multiple, densely interwoven neurons is much more challenging. Here the authors develop G-Cut, a computational approach for accurate segmentation of densely interconnected neuron clusters.

    • Rui Li
    • Muye Zhu
    • Hong-Wei Dong
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12
  • The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

    • Edward M. Callaway
    • Hong-Wei Dong
    • Susan Sunkin
    ResearchOpen Access
    Nature
    Volume: 598, P: 86-102
  • Sparse labelling and whole-brain imaging are used to reconstruct and classify brain-wide complete morphologies of 1,741 individual neurons in the mouse brain, revealing a dependence on both brain region and transcriptomic profile.

    • Hanchuan Peng
    • Peng Xie
    • Hongkui Zeng
    ResearchOpen Access
    Nature
    Volume: 598, P: 174-181