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Showing 1–2 of 2 results
Advanced filters: Author: Matthew D. Maletic Clear advanced filters
  • Using biochemistry, chemical biology, and cryo-EM, Maiwald et al. elucidate how TRIP12 forms K29 linkages and K29/K48-linked branched ubiquitin chains, revealing a mechanism for polyubiquitylation shared by some HECT E3s.

    • Samuel A. Maiwald
    • Laura A. Schneider
    • Brenda A. Schulman
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 32, P: 1766-1775
  • SUMO modification regulates protein function, with SENP enzymes controlling SUMO removal. Here, the authors present crystal structures of SENP5 bound to SUMO1 and SUMO2, revealing how structural features drive its preference for SUMO2 and offering insights into SUMOylation regulation.

    • Lucía Sánchez-Alba
    • Li Ying
    • David Reverter
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13