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Showing 1–7 of 7 results
Advanced filters: Author: Matthew S. Bramble Clear advanced filters

  • The search for biomarkers associated with konzo disease has been a long-standing question within the research community. Here, the authors have uncovered a potential biomarker for konzo that is associated with the ability to manage oxidative damage.

    • Matthew S. Bramble
    • Victor Fourcassié
    • Arnaud Droit
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Here, using metagenomic profiling in 180 individuals from the Democratic Republic of the Congo, the authors find associations between the gut microbiome and konzo, a neurodegenerative disease that mostly affects children and is caused by the consumption improperly processed cassava.

    • Matthew S. Bramble
    • Neerja Vashist
    • Eric Vilain
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Acromyrmex ants cultivate fungus gardens that can be parasitized by Escovopsis sp., leading to colony collapse. Here, Heine et al. identify two secondary metabolites produced by Escovopsis that accumulate in Acromyrmex tissue, reduce behavioural defenses and suppress symbiotic Pseudonocardia bacteria.

    • Daniel Heine
    • Neil A. Holmes
    • Barrie Wilkinson
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • Using realistic simulations, statistical methods to integrate microbiome and metabolome data are assessed and those best suited for different tasks are identified. Recommendations for method selection depending on the aim and data structure are provided.

    • Loïc Mangnier
    • Antoine Bodein
    • Arnaud Droit
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-17

  • Regular physical activity reduces the risk of chronic disease and mortality, but the mechanisms underpinning this protective effect are poorly understood. Here, Kim et al. review candidate genes and pathways implicated in human performance by genetic, genomic and multi-omic studies.

    • Daniel Seung Kim
    • Matthew T. Wheeler
    • Euan A. Ashley
    Reviews
    Nature Reviews Genetics
    Volume: 23, P: 40-54