Human cytomegalovirus (HCMV) infection is ordinarily controlled by a vigorous immune response; however, HCMV can replicate to high levels and cause end organ disease when the immune system is compromised. In this Review, Griffiths and Reeves discuss HCMV pathogenesis in immunocompromised individuals and emerging strategies to treat and prevent infection and disease.
- Paul Griffiths
- Matthew Reeves
