Recent work has revealed that dendritic cells (DCs) are more heterogeneous than previously thought, yet the functional roles of these newly described DC subsets remain unclear. Here, Li et al. find that in mice, TSLP from keratinocytes activates transitional DC-derived DC2 to promote GATA3+ regulatory T cells and mediate immunosuppression during inflammation and cancer.
- Marine Guivarch
- Pierre Meyer
- Mei Li
