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The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity

The first X-ray crystal structure of a hetero-tetrameric septin complex is presented. From this a novel hydrophobic structural element conserved in septins from yeast to man is identified and characterized.

Benjamin Grupp
Lukas Denkhaus
Thomas Gronemeyer
ResearchOpen Access06 Jan 2024
Communications Biology

Volume: 7, P: 1-15

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The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity

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