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Showing 1–3 of 3 results
Advanced filters: Author: Maxim Mayzel Clear advanced filters

  • Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimer´s disease. Here authors present the 3D- structure of an Aβ oligomer formed in a membrane mimicking environment and observe that Aβ tetramers and octamers inserted into lipid bilayers as well-defined pores.

    • Sonia Ciudad
    • Eduard Puig
    • Natàlia Carulla
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Classical toxin–antitoxin systems in bacteria are based on silencing of a toxin by an antitoxin that, when inactivated, releases the toxin, resulting in a change in metabolism. Here, the authors characterize an oxygen-sensitive toxin–antitoxin system and discuss the implications for the role of the Hha antitoxin.

    • Oriol Marimon
    • João M. C. Teixeira
    • Miquel Pons
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-10