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Showing 1–4 of 4 results
Advanced filters: Author: Maxime De Waegeneer Clear advanced filters

  • This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal regulator of mitochondrial morphology and function, critical for activity-dependent synaptic connectivity.

    • Iryna Mohylyak
    • Maheva Andriatsilavo
    • Bassem A. Hassan
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • A chromatin accessibility atlas of 240,919 cells in the adult and developing Drosophila brain reveals 95,000 enhancers, which are integrated in cell-type specific enhancer gene regulatory networks and decoded into combinations of functional transcription factor binding sites using deep learning.

    • Jasper Janssens
    • Sara Aibar
    • Stein Aerts
    Research
    Nature
    Volume: 601, P: 630-636

  • SCENIC is a computational pipeline to predict cell-type-specific transcription factors through network inference and motif enrichment. Here the authors describe a detailed protocol for pySCENIC: a faster, container-based implementation in Python.

    • Bram Van de Sande
    • Christopher Flerin
    • Stein Aerts
    Protocols
    Nature Protocols
    Volume: 15, P: 2247-2276