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Showing 1–3 of 3 results
Advanced filters: Author: Maxwell Sanderford Clear advanced filters
  • Researchers can make use of a variety of computational tools to prioritize genetic variants and predict their pathogenicity. Here, the authors evaluate the performance of six of these tools in three typical biological tasks and find generally low concordance of predictions and experimental confirmation.

    • Li Liu
    • Maxwell D. Sanderford
    • Sudhir Kumar
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11
  • In convergent trait evolution, similar genetic changes may occur independently, which can help to pinpoint biological mechanisms. Here, the authors present a machine learning technique that links genes to convergent phenotypes, revealing strong enrichments of hearing-related proteins underlying echolocation in mammals.

    • John B. Allard
    • Sudip Sharma
    • Sudhir Kumar
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14