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Showing 1–13 of 13 results
Advanced filters: Author: Maya L. Gomes Clear advanced filters

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • Present et al. examine the processes controlling lithification of microbial mats in a Caribbean peritidal carbonate environment. The authors present sedimentological and geochemical evidence of a surprising bias against preserving the most robust, widespread microbial ecosystems in the sedimentary record.

    • Theodore M. Present
    • Maya L. Gomes
    • John P. Grotzinger
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8

  • The mechanisms responsible for the burial of vast quantities of organic matter during Ocean Anoxic Event remain unclear. Here, the authors combine biogeochemical analysis and modeling and show that sulfurization could play a critical role in facilitating globally elevated burial of organic matter.

    • Morgan Reed Raven
    • David A. Fike
    • Harry-Luke O. McClelland
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9

  • The internal organization of the cell has been enriched by the discovery that organelles establish membrane contact sites, however the entire repertoire of these contacts is still being explored. Here the authors systematically identify the landscape of cellular contact sites in yeast, discovering four potential novel contact sites and two tether proteins for the peroxisome-mitochondria contact site.

    • Nadav Shai
    • Eden Yifrach
    • Einat Zalckvar
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • The first of two stepwise increases in atmospheric oxygen occurred at the end of the Archaean eon. Analyses of sulfur and iron isotopes in pyrite reveal a near-shore environment that hosted locally oxygenated conditions in the Mesoarchaean era.

    • Maya L. Gomes
    News & Views
    Nature Geoscience
    Volume: 11, P: 84-85

  • The redox transformations of sulfur mean it is a key component of global biogeochemical cycles. This Review explores the sulfur cycle over geological time, including its role during major climate perturbations, oceanic anoxic events and the evolution of life.

    • Mojtaba Fakhraee
    • Peter W. Crockford
    • Noah Planavsky
    Reviews
    Nature Reviews Earth & Environment
    Volume: 6, P: 106-125